The first menstrual cycle of girls is usually an unpleasant experience because with nervousness, embarrassment about body changes and changes. Psychology and mood are associated. It seems that awareness of the changes of this period can affect the positive and negative attitudes and practices about it and cause the physical and mental health of girls. Therefore, the aim of the present study was to study the lived experience of gifted female students from their menstrual period. Data were collected through in-depth and semi-structured interviews with 15 gifted 10th grade female students by purposive sampling and analyzed using open coding method. The main and secondary themes were extracted from data analysis. Girls students’ lived experience in three categories of premenstrual experience (with subcategories of riddles of consciousness and contradictory feelings), first experience (subconscious predictors of disappearance, shock of happiness and fear, information seeking, family support and vital tools) and Postmenstrual experiences (The growth of caregivers and caregivers, Disruption of individual and social life and multiple transpersonal encounters with menstruation). As a result, girls 'lived experience shows that increasing students' awareness of menstruation makes them more aware of the mental and physical problems of this period and have a greater ability to overcome them. It is suggested that by holding family education sessions by gynecologists for female students and for their parents, especially mothers, make useful medical programs by radio, improve the content of textbooks with the conditions of menstruation and Etc. She made them aware of the importance of their health.